CannaSearch Daily on CBD + Hemp

Oregon hemp farmers retrench in 2020

Oregon hemp farmers retrench in 2020 Rick Bush, a hemp farmer and processor in Salem, Ore., said he personally uses the cannabidiol, or CBD, extracted from hemp for health reasons and … Oregon <b>hemp</b> farmers retrench in 2020 https://www.google.com/url?rct=j&sa=t&url=https://www.capitalpress.com/state/oregon/oregon-hemp-farmers-retrench-in-2020/article_e152cca8-784c-11ea-8104-97aae718a5c3.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNE2Ie0SpgNQnD4ENuDpi_hpz5tOSw April 6, 2020 10:52 pm #CBD #Hemp

7th Circ. Told New State Law Doesn't Fix Smokable Hemp Ban

7th Circ. Told New State Law Doesn't Fix Smokable Hemp Ban Law360 (April 6, 2020, 6:10 PM EDT) — A group of CBD companies challenging Indiana's smokable hemp ban has told the Seventh Circuit that a new … 7th Circ. Told New State Law Doesn't Fix Smokable <b>Hemp</b> Ban https://www.google.com/url?rct=j&sa=t&url=https://www.law360.com/illinois/articles/1260753/7th-circ-told-new-state-law-doesn-t-fix-smokable-hemp-ban&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNE1V39XhytDO3u94jJypDD9ML6GSw April 6, 2020 10:07 pm #CBD #Hemp

How CBD can help you relax and de-stress (and where to order it)

How CBD can help you relax and de-stress (and where to order it) CBD, short for cannabidiol, is also said to help with chronic pain and makes falling asleep easier. CBD products do not produce a high, because each … How <b>CBD</b> can help you relax and de-stress (and where to order it) https://www.google.com/url?rct=j&sa=t&url=https://www.mlive.com/life/2020/04/how-cbd-can-help-you-relax-and-de-stress-and-where-to-order-it.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNE60Lmul1aocgNLKgMQLoyUSJmwQQ April 6, 2020 9:45 pm #CBD #Hemp

Everything To Know About Those Pet CBD Products

Everything To Know About Those Pet CBD ProductsCBD, and the terpenes [natural components of hemp that provide the plant's color, smell, and flavor] found in the hemp plant, are powerful molecules … Everything To Know About Those Pet <b>CBD</b> Products https://www.google.com/url?rct=j&sa=t&url=https://www.yahoo.com/lifestyle/everything-know-those-pet-cbd-211056965.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNECJTZahCnHdwBVac-FxsOjwtPlzQ April 6, 2020 9:11 pm #CBD #Hemp

Kats Botanicals Announces a New Line of CBD Oils and an Update Packaging and GMP Certification

Kats Botanicals Announces a New Line of CBD Oils and an Update Packaging and GMP Certification CBD isolate is 99% pure CBD without any cannabinoids or terpenes, making it a safe option for workers who are regularly drug tested. CBD salves may … Kats Botanicals Announces a New Line of <b>CBD</b> Oils and an Update Packaging and GMP Certification https://www.google.com/url?rct=j&sa=t&url=https://menafn.com/1099980852/Kats-Botanicals-Announces-a-New-Line-of-CBD-Oils-and-an-Update-Packaging-and-GMP-Certification&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHrAehFedjQkhUm49pix9XMZeicvA April 6, 2020 9:00 pm #CBD #Hemp

Cbd Kc

Cbd Kc Then cbd kc It will be very exciting. The fishing Cbd Kc boat was shaking in the waves, floating and changing. Thorne said. Malcolm shrugged. hemp … <b>Cbd</b> Kc https://www.google.com/url?rct=j&sa=t&url=https://www.mosquefoundation.org/cbd-oil/cbd-kc&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNE7JygceLR5t98Qg96GwksJIE4adg April 6, 2020 8:23 pm #CBD #Hemp

DEA relaxes rules for the only federally approved drug derived from marijuana

DEA relaxes rules for the only federally approved drug derived from marijuana Epidiolex is a purified form of cannabidiol, or CBD, extracted from the marijuana plant. Related … It remains the only CBD drug approved by the FDA. DEA relaxes rules for the only federally approved drug derived from marijuana https://www.google.com/url?rct=j&sa=t&url=https://www.inquirer.com/business/weed/epidiolex-cbd-cannabidiol-gw-pharma-roark-dea-fda-20200406.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGSf3AjCp8eT0-8t-VDlh7YjNapbQ April 6, 2020 7:56 pm #CBD #Hemp

CBD store owner accused of defrauding investors in SEC complaint

CBD store owner accused of defrauding investors in SEC complaint The co-founder of a defunct Connecticut holding company and CBD and hemp store has been charged by the Securities and Exchange Commission … <b>CBD</b> store owner accused of defrauding investors in SEC complaint https://www.google.com/url?rct=j&sa=t&url=https://hempindustrydaily.com/cbd-store-owner-accused-of-defraiding-investors-in-sec-complaint/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHNTMTPJV_DfW7vZSWyX7LbAzN4wA April 6, 2020 7:41 pm #CBD #Hemp

Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users.

Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users.

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Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users.

Drug Alcohol Depend. 2020 Mar 12;:107937

Authors: Spindle TR, Cone EJ, Goffi E, Weerts EM, Mitchell JM, Winecker RE, Bigelow GE, Flegel RR, Vandrey R

Abstract
INTRODUCTION: The use and availability of oral and inhalable products containing cannabidiol (CBD) as the principal constituent has increased with expanded cannabis/hemp legalization. However, few controlled clinical laboratory studies have evaluated the pharmacodynamic effects of oral or vaporized CBD or CBD-dominant cannabis.
METHODS: Eighteen healthy adults (9 men; 9 women) completed four, double-blind, double-dummy, drug administration sessions. Sessions were separated by ≥1 week and included self-administration of 100 mg oral CBD, 100 mg vaporized CBD, vaporized CBD-dominant cannabis (100 mg CBD; 3.7 mg THC), and placebo. Study outcomes included: subjective drug effects, vital signs, cognitive/psychomotor performance, and whole blood THC and CBD concentrations.
RESULTS: Vaporized CBD and CBD-dominant cannabis increased ratings on several subjective items (e.g., Like Drug Effect) relative to placebo. Subjective effects did not differ between oral CBD and placebo and were generally higher for CBD-dominant cannabis compared to vaporized CBD. CBD did not increase ratings for several items typically associated with acute cannabis/THC exposure (e.g., Paranoid). Women reported qualitatively higher ratings for Pleasant Drug Effect than men after vaporized CBD and CBD-dominant cannabis use. CBD-dominant cannabis increased heart rate compared to placebo. Cognitive/psychomotor impairment was not observed in any drug condition.
CONCLUSIONS: Vaporized CBD and CBD-dominant cannabis produced discriminable subjective drug effects, which were sometimes stronger in women, but did not produce cognitive/psychomotor impairment. Subjective effects of oral CBD did not differ from placebo. Future research should further elucidate the subjective effects of various types of CBD products (e.g., inhaled, oral, topical), which appear to be distinct from THC-dominant products.

PMID: 32247649 [PubMed – as supplied by publisher]

Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users. https://www.ncbi.nlm.nih.gov/pubmed/32247649?dopt=Abstract #CBD #Hemp

Prebiotic potential of hemp blended drinks fermented by probiotics.

Prebiotic potential of hemp blended drinks fermented by probiotics.

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Prebiotic potential of hemp blended drinks fermented by probiotics.

Food Res Int. 2020 May;131:109029

Authors: Nissen L, di Carlo E, Gianotti A

Abstract
Plant-based drinks as substitute for milk consumption are raising striking interest in the food industry. Soy and rice drinks are the most studied and successful milk substitutes. An untapped source is hemp seed, which is a powerhouse of nutrients bearing bioactive compounds, but the production of derived drink is limited. The present work is about introducing new formulations of commercial hemp seed-derived drink to be fermented with probiotics (Lactobacillus fermentum, Lb. plantarum and Bifidobacterium bifidum). In this work for the first time the prebiotic activity of different hemp seed drinks was assessed by cultural and quantitative PCR methods. In addition, to better describe the prebiotic potential, VOCs alkenes and volatile organic acids were characterized by a metabolomic approach via GC-MS SPME. Obtained results showed that the hemp seed drinks had strong prebiotic activity, ability to support probiotics growth and to increase the content of some bioactive compounds. These outputs are in part due to the presence of different terpenes that inhibit the growth of enteropathogens and to high levels of acetate, propionate and butyrate produced during fermentation that support the growth of probiotics. Although the health potential of hemp seed is well known, derived drinks are hitherto scarcely transformed and distributed, thus this work could provide some basics to produce prebiotic and probiotic fermented hemp seed drinks.

PMID: 32247454 [PubMed – as supplied by publisher]

Prebiotic potential of hemp blended drinks fermented by probiotics. https://www.ncbi.nlm.nih.gov/pubmed/32247454?dopt=Abstract #Hemp

Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users.

Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users.

Icon for Elsevier Science Related Articles

Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users.

Drug Alcohol Depend. 2020 Mar 12;:107937

Authors: Spindle TR, Cone EJ, Goffi E, Weerts EM, Mitchell JM, Winecker RE, Bigelow GE, Flegel RR, Vandrey R

Abstract
INTRODUCTION: The use and availability of oral and inhalable products containing cannabidiol (CBD) as the principal constituent has increased with expanded cannabis/hemp legalization. However, few controlled clinical laboratory studies have evaluated the pharmacodynamic effects of oral or vaporized CBD or CBD-dominant cannabis.
METHODS: Eighteen healthy adults (9 men; 9 women) completed four, double-blind, double-dummy, drug administration sessions. Sessions were separated by ≥1 week and included self-administration of 100 mg oral CBD, 100 mg vaporized CBD, vaporized CBD-dominant cannabis (100 mg CBD; 3.7 mg THC), and placebo. Study outcomes included: subjective drug effects, vital signs, cognitive/psychomotor performance, and whole blood THC and CBD concentrations.
RESULTS: Vaporized CBD and CBD-dominant cannabis increased ratings on several subjective items (e.g., Like Drug Effect) relative to placebo. Subjective effects did not differ between oral CBD and placebo and were generally higher for CBD-dominant cannabis compared to vaporized CBD. CBD did not increase ratings for several items typically associated with acute cannabis/THC exposure (e.g., Paranoid). Women reported qualitatively higher ratings for Pleasant Drug Effect than men after vaporized CBD and CBD-dominant cannabis use. CBD-dominant cannabis increased heart rate compared to placebo. Cognitive/psychomotor impairment was not observed in any drug condition.
CONCLUSIONS: Vaporized CBD and CBD-dominant cannabis produced discriminable subjective drug effects, which were sometimes stronger in women, but did not produce cognitive/psychomotor impairment. Subjective effects of oral CBD did not differ from placebo. Future research should further elucidate the subjective effects of various types of CBD products (e.g., inhaled, oral, topical), which appear to be distinct from THC-dominant products.

PMID: 32247649 [PubMed – as supplied by publisher]

Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users. https://www.ncbi.nlm.nih.gov/pubmed/32247649?dopt=Abstract #Hemp

Potential Mechanisms Involved in Palmitoylethanolamide-Induced Vasodepressor Effects in Rats.

Potential Mechanisms Involved in Palmitoylethanolamide-Induced Vasodepressor Effects in Rats.

Related Articles

Potential Mechanisms Involved in Palmitoylethanolamide-Induced Vasodepressor Effects in Rats.

J Vasc Res. 2020 Apr 03;:1-12

Authors: Marichal-Cancino BA, González-Hernández A, MaassenVanDenBrink A, Ramírez-San Juan E, Villalón CM

Abstract
Palmitoylethanolamide is an endogenous lipid that exerts complex vascular effects, enhances the effects of endocannabinoids and induces a direct hypotension, but the mechanisms involved have been poorly explored. Hence, this study investigated in Wistar pithed rats the role of CB1, CB2, TRPV1 and GPR55 receptors in the inhibition by palmitoylethanolamide of the vasopressor responses produced by sympathetic stimulation or exogenous noradrenaline. Frequency- and dose-dependent vasopressor responses were analysed before and during intravenous (i.v.) continuous infusions of palmitoylethanolamide in animals receiving i.v. bolus of the antagonists NIDA41020 (CB1), AM630 (CB2), capsazepine (TRPV1), and/or cannabidiol (GPR55). Palmitoyletha-nolamide (0.1-3.1 μg/kg/min) dose-dependently inhibited the sympathetically induced and noradrenaline-induced vasopressor responses. Both inhibitions were: (i) partially blocked by 100 μg/kg NIDA41020, 100 μg/kg capsazepine, or 31 μg/kg cannabidiol; (ii) unaffected by 310 μg/kg AM630; and (iii) abolished by the combination NIDA41020 + capsazepine + cannabidiol (100, 100, and 31 μg/kg, respectively). The resting blood pressure was decreased by palmitoylethanolamide (effect prevented by NIDA41020, capsazepine or cannabidiol, but not by AM630). These results suggest that: (i) palmitoylethanolamide inhibits the vasopressor responses to sympathetic stimulation and exogenous noradrenaline and that it induces hypotension; and (ii) all these effects are mediated by prejunctional and vascular CB1, TRPV1 and probably GPR55, but not by CB2, receptors.

PMID: 32248195 [PubMed – as supplied by publisher]

Potential Mechanisms Involved in Palmitoylethanolamide-Induced Vasodepressor Effects in Rats. https://www.ncbi.nlm.nih.gov/pubmed/32248195?dopt=Abstract #CBD #Hemp

Top 6 ways to protect a cannabis business brand

Top 6 ways to protect a cannabis business brand This means that the only CBD products eligible for federal trademark … deep business expertise and relevant cannabis/hemp industry experience to … Top 6 ways to protect a cannabis business brand https://www.google.com/url?rct=j&sa=t&url=https://www.bizjournals.com/portland/news/2020/04/06/top-6-ways-to-protect-a-cannabis-business-brand.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEzgl7leh7aCrXRXYHE3g_IzYcaMQ April 6, 2020 7:18 pm #CBD #Hemp

Canna Nature Labs: High Quality Premium Topical Hemp CBD Cream?

Canna Nature Labs: High Quality Premium Topical Hemp CBD Cream? 100% Hemp Cream by Canna Nature Labs is a topical remedy that is meant to promote pain relief and to reduce stress. The formula can be found on … Canna Nature Labs: High Quality Premium Topical <b>Hemp CBD</b> Cream? https://www.google.com/url?rct=j&sa=t&url=https://timesofcbd.com/canna-nature-labs/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEwER4sCr38EAn9Em7fLM-z-Omg8A April 6, 2020 6:33 pm #CBD #Hemp

The DEA Has Descheduled Prescription CBD for Severe Epilepsy

The DEA Has Descheduled Prescription CBD for Severe Epilepsy Epidiolex's active ingredient is CBD derived from marijuana, not hemp. Cannabidiol under a hand lens. Image source: Getty Images. The DEA placed … The DEA Has Descheduled Prescription <b>CBD</b> for Severe Epilepsy https://www.google.com/url?rct=j&sa=t&url=https://www.fool.com/investing/2020/04/06/the-dea-descheduled-prescription-cbd-for-severe-ep.aspx&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFh4k6g_d2DPUfFRlxidErwaECpNg April 6, 2020 6:22 pm #CBD #Hemp

CO2 GRO Inc. Announces the Completion of Fifteen Hemp Greenhouse Installations in Missouri

CO2 GRO Inc. Announces the Completion of Fifteen Hemp Greenhouse Installations in Missouri As press released previously on February 12, 2020, Linn County and Sacred Seeds work with nearly 250 contracted hemp greenhouses across … CO2 GRO Inc. Announces the Completion of Fifteen <b>Hemp</b> Greenhouse Installations in Missouri https://www.google.com/url?rct=j&sa=t&url=https://finance.yahoo.com/news/co2-gro-inc-announces-completion-163000824.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHpt6IbYhNIKSOX6sJHwHktOTLfVw April 6, 2020 4:30 pm #CBD #Hemp

Where is the CBD Market Headed?

Where is the CBD Market Headed? CBD doesn't get you high, and industrial hemp must contain less than 0.3% THC to even be legally grown or cultivated. CBD has been found to offer … Where is the <b>CBD</b> Market Headed? https://www.google.com/url?rct=j&sa=t&url=https://www.bigeasymagazine.com/2020/04/06/where-is-the-cbd-market-headed/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEuw7OomDUylUy_MhE-GK0YSW_EBQ April 6, 2020 4:07 pm #CBD #Hemp

CBD Hemp Oil Market Trends Analysis, Top Manufacturers, Shares, Growth Opportunities and …

CBD Hemp Oil Market Trends Analysis, Top Manufacturers, Shares, Growth Opportunities and … New Jersey, United States: Verified Market Research has added a new research report titled, 'CBD Hemp Oil Market Professional Survey Report … <b>CBD Hemp</b> Oil Market Trends Analysis, Top Manufacturers, Shares, Growth Opportunities and ... https://www.google.com/url?rct=j&sa=t&url=https://germanyenglishnews.com/german-news/2020/04/06/cbd-hemp-oil-market-trends-analysis-top-manufacturers-shares-growth-opportunities-and-forecast-to-2026/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGI0br3h8C5EQTHbmulHcPTtfrdQA April 6, 2020 3:46 pm #CBD #Hemp

Hemp and the pitfalls of the USDA's Interim Final Rule

Hemp and the pitfalls of the USDA's Interim Final Rule Given the broad range of applications of hemp and the ever-evolving mania for hemp-derived cannabinoids (CBD, CBG, CBN), farmers across the … <b>Hemp</b> and the pitfalls of the USDA's Interim Final Rule https://www.google.com/url?rct=j&sa=t&url=https://www.bizjournals.com/portland/news/2020/04/06/hemp-and-the-pitfalls-of-the-usda-s-interim-final.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEaK_LrKboXPFYXJG3HYkHx5C5szg April 6, 2020 3:11 pm #CBD #Hemp

Historic hemp records donated to University of Kentucky

Historic hemp records donated to University of Kentucky The university's Special Collections Library will clean and archive the papers, said Daniel Isenstein, president of advocacy group Hemp Highway of … Historic <b>hemp</b> records donated to University of Kentucky https://www.google.com/url?rct=j&sa=t&url=https://hempindustrydaily.com/historic-hemp-records-donated-to-university-of-kentucky/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEW8vvkqESXueSFwipJnceSNBl-1A April 6, 2020 3:00 pm #CBD #Hemp

Black Dog and partners establish LED-centric hemp research facility

Black Dog and partners establish LED-centric hemp research facility The plant has many uses, although the highest value of those is production of cannabinoids including CBD (cannabidiol), CBG (cannabigerol), and CBN … Black Dog and partners establish LED-centric <b>hemp</b> research facility https://www.google.com/url?rct=j&sa=t&url=https://www.ledsmagazine.com/horticultural-lighting/article/14173451/black-dog-and-partners-establish-ledcentric-hemp-research-facility&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEUMRr0DS5lNQF46EiLazNB-wY5Fw April 6, 2020 2:37 pm #CBD #Hemp

Love Hemp launches Love Hemp Immune

Love Hemp launches Love Hemp Immune Made with the highest quality ingredients, including a combination of CBD, Vitamin C, Vitamin D and Bilberry extract, Love Hemp Immune contains all … Love <b>Hemp</b> launches Love <b>Hemp</b> Immune https://www.google.com/url?rct=j&sa=t&url=http://www.retailtimes.co.uk/love-hemp-launches-love-hemp-immune/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFu3nQ96yz0nqpyJKEMpLOcGH2oww April 6, 2020 1:52 pm #CBD #Hemp

Global Cannabinoids Pivots from CBD to Hand Sanitizer in Response to COVID-19 Crisis

Global Cannabinoids Pivots from CBD to Hand Sanitizer in Response to COVID-19 Crisis The company, which has been one of the largest wholesale retailers of American-grown hemp and CBD, has transitioned its operations to hand … Global Cannabinoids Pivots from <b>CBD</b> to Hand Sanitizer in Response to COVID-19 Crisis https://www.google.com/url?rct=j&sa=t&url=https://www.cannabisdispensarymag.com/global-cannabinoids-pivots-from-cbd-to-hand-sanitizer-covid-19.aspx&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFhBMWyA6OtNl-qLIjGcs053mrHpA April 6, 2020 1:30 pm #CBD #Hemp

HempAmericana, Inc. Discusses Their New eCommerce Platform with The Stock Day Podcast

HempAmericana, Inc. Discusses Their New eCommerce Platform with The Stock Day Podcast HempAmericana is an emerging leader in the CBD products market. … including a popular brand of hemp rolling papers marketed under the brand … HempAmericana, Inc. Discusses Their New eCommerce Platform with The Stock Day Podcast https://www.google.com/url?rct=j&sa=t&url=https://finance.yahoo.com/news/hempamericana-inc-discusses-ecommerce-platform-130000412.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGY6D8sJQClFNViAG060HUjy9fzhQ April 6, 2020 1:07 pm #CBD #Hemp

Can B Corp Announces Fourth Quarter and Full Year 2019 Results

Can B Corp Announces Fourth Quarter and Full Year 2019 Results Deployed Initial CBD Vending Machines; Launched First Capsule Hemp Extract Product; Created Fully Independent Board of Directors. Key Financial … Can B Corp Announces Fourth Quarter and Full Year 2019 Results https://www.google.com/url?rct=j&sa=t&url=https://finance.yahoo.com/news/b-corp-announces-fourth-quarter-130010521.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFrLDXTbXgOQ0-Tosuhq_LvHtIRbw April 6, 2020 12:56 pm #CBD #Hemp

GW Pharmaceuticals plc and Its US Subsidiary Greenwich Biosciences, Inc. Announce That …

GW Pharmaceuticals plc and Its US Subsidiary Greenwich Biosciences, Inc. Announce That … “This notification from DEA fully establishes that EPIDIOLEX, the only CBD … The Company's lead product, EPIDIOLEX® (cannabidiol) oral solution, … GW Pharmaceuticals plc and Its US Subsidiary Greenwich Biosciences, Inc. Announce That ... https://www.google.com/url?rct=j&sa=t&url=https://finance.yahoo.com/news/gw-pharmaceuticals-plc-u-subsidiary-130010119.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHMRmmYOGyAG7IuXRUGHv99TVCTlw April 6, 2020 12:56 pm #CBD #Hemp

Hemp vs Cotton: Which Fabric Is Better For The Environment?

Hemp vs Cotton: Which Fabric Is Better For The Environment? But does being the most used fiber for clothing worldwide make it the best option? Hemp, on the other hand, doesn't know the same popularity. But … <b>Hemp</b> vs Cotton: Which Fabric Is Better For The Environment? https://www.google.com/url?rct=j&sa=t&url=https://www.greenmarketreport.com/hemp-vs-cotton-which-fabric-is-better-for-the-environment/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNG1nPovXAXwfNEpdGscxXYpXui9dg April 6, 2020 12:45 pm #CBD #Hemp

Heritage Cannabis subsidiary Cannacure wins industrial hemp license from Health Canada

Heritage Cannabis subsidiary Cannacure wins industrial hemp license from Health Canada The license will allow Cannacure to bulk store and sell industrial hemp, … growing hemp and CBD markets,” said CEO Clint Sharples in a statement. Heritage Cannabis subsidiary Cannacure wins industrial <b>hemp</b> license from Health Canada https://www.google.com/url?rct=j&sa=t&url=https://www.proactiveinvestors.com/companies/news/916708/heritage-cannabis-subsidiary-cannacure-wins-industrial-hemp-license-from-health-canada-916708.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFzI_prm-4MZdcUs13H7ps3kI1W9g April 6, 2020 12:33 pm #CBD #Hemp

cbdMD Provides Preliminary Q2 Sales Results

cbdMD Provides Preliminary Q2 Sales Results (NYSE American: YCBD, YCBD PR A), a leading cannabidiol (CBD) consumer brand, announced today that its preliminary year over year sales for the … cbdMD Provides Preliminary Q2 Sales Results https://www.google.com/url?rct=j&sa=t&url=https://www.businesswire.com/news/home/20200406005072/en/cbdMD-Preliminary-Q2-Sales-Results&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGhAAm9WFOf6HTUiJBIwzaUgpuDIg April 6, 2020 11:26 am #CBD #Hemp

Heritage Cannabis Holdings Corp. Subsidiary Cannacure Receives Industrial Hemp License From …

Heritage Cannabis Holdings Corp. Subsidiary Cannacure Receives Industrial Hemp License From … Heritage (CSE:CANN) announces its subsidiary Cannacure has been granted an industrial hemp license by Health Canada, effective April 3, 2020 to … Heritage Cannabis Holdings Corp. Subsidiary Cannacure Receives Industrial <b>Hemp</b> License From ... https://www.google.com/url?rct=j&sa=t&url=https://investingnews.com/daily/cannabis-investing/heritage-cannabis-holdings-corp.subsidiary-cannacure-receives-industrial-hemp-license-from-health-canada/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEddu26IbknpUYJREuTW-ogvtYMhA April 6, 2020 11:03 am #CBD #Hemp

Virtuality Reality Races: Expect The Unexpected

Virtuality Reality Races: Expect The Unexpected cbd oil: cbd lube can cbd help migraines is cbd oil safe for kids do all the good you can cbd hemp field terra pure cbd oil sol cbd balm nature made … Virtuality Reality Races: Expect The Unexpected https://www.google.com/url?rct=j&sa=t&url=https://www.northcountrypublicradio.org/news/npr/827922259/virtuality-reality-races-expect-the-unexpected&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGMdLPUJEx0AfZqbb20szLaV6uc1Q April 6, 2020 9:56 am #CBD #Hemp

State takes over SC-grown hemp tests to ensure THC levels aren't too high

State takes over SC-grown hemp tests to ensure THC levels aren't too high The task of testing hemp for for its primary psychoactive compound will now have to be handled by state inspectors rather than growers under a … State takes over SC-grown <b>hemp</b> tests to ensure THC levels aren't too high https://www.google.com/url?rct=j&sa=t&url=https://www.postandcourier.com/business/state-takes-over-sc-grown-hemp-tests-to-ensure-thc-levels-arent-too-high/article_fa0f1d24-706c-11ea-a4e4-0f5562544473.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEuGWWLIGK88nPXWlcUnOfHvbhLDw April 6, 2020 9:56 am #CBD #Hemp

Icelandic Police Drop Charges Against Hemp Farmers

Icelandic Police Drop Charges Against Hemp Farmers Police have dropped charges against farmers in Gautavík, East Iceland who are cultivating industrial hemp, RÚV reports. The plant is derived from a … Icelandic Police Drop Charges Against <b>Hemp</b> Farmers https://www.google.com/url?rct=j&sa=t&url=https://www.icelandreview.com/news/icelandic-police-drop-charges-against-hemp-farmers/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNG_Hz6G9kaQ_MMhE1r2R3du7ovq1A April 6, 2020 9:45 am #CBD #Hemp

When You Work In Construction, Social Distancing Isn't Always Possible

When You Work In Construction, Social Distancing Isn't Always Possible cbd oil: cbd cream for sale near me best reviewed cbd oil cbd oil png … cannabis oil for pain hempys cbd best hemp products mountain cbd cbd oil … When You Work In Construction, Social Distancing Isn't Always Possible https://www.google.com/url?rct=j&sa=t&url=https://www.northcountrypublicradio.org/news/npr/827922315/when-you-work-in-construction-social-distancing-isn-t-always-possible&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFNe1YNCknUCt3ApiJysaiBqVHbBA April 6, 2020 9:00 am #CBD #Hemp

The OG 'Big Brother' Narrator Talks Us Through Another Day In Isolation

The OG 'Big Brother' Narrator Talks Us Through Another Day In Isolation What Is Hemp Seed Oil? Well, it's not the same as CBD oil, which can make you high. Hemp seed oil is made directly from the seeds, not the … The OG 'Big Brother' Narrator Talks Us Through Another Day In Isolation https://www.google.com/url?rct=j&sa=t&url=https://www.pedestrian.tv/entertainment/bootleg-big-brother/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNENQNnQmQAzwpEyQ6bT8IVKIYvfDQ April 6, 2020 7:30 am #CBD #Hemp

I'm Currently Obsessed With Hemp Seed Oil For Calming My Psycho Self Isolation Skin

I'm Currently Obsessed With Hemp Seed Oil For Calming My Psycho Self Isolation Skin My skin seems to LOVE hemp seed! It's in a relationship with it! 1. What Is Hemp Seed Oil? Well, it's not the same as CBD oil, which can … I'm Currently Obsessed With <b>Hemp</b> Seed Oil For Calming My Psycho Self Isolation Skin https://www.google.com/url?rct=j&sa=t&url=https://www.pedestrian.tv/style/hemp-seed-oil/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHYdMDbnqCWhJq4JJIGOgzTAYGCiA April 6, 2020 7:18 am #CBD #Hemp

Bankruptcy and restructuring in the cannabis industry in 2020 and beyond

Bankruptcy and restructuring in the cannabis industry in 2020 and beyond In short, CBD and hemp businesses and those that deal with them may be able to seek protection of federal bankruptcy courts in the Ninth Circuit. [1] … Bankruptcy and restructuring in the cannabis industry in 2020 and beyond https://www.google.com/url?rct=j&sa=t&url=https://www.bizjournals.com/portland/news/2020/04/06/bankruptcy-and-restructuring-in-the-cannabis.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHVosUtpsoFdbDm9N1sY3hlyU41-g April 6, 2020 6:56 am #CBD #Hemp

Best CBD Cream for Pain

Best CBD Cream for Pain Unlike most of the other providers on the list, Lazarus Naturals offer only full-spectrum hemp extract in their CBD balm. That means that besides CBD, … Best <b>CBD</b> Cream for Pain https://www.google.com/url?rct=j&sa=t&url=https://www.sfexaminer.com/marketplace/best-cbd-cream-for-pain/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNE2YWBfQxWHJeCHfwwrNDS4o8NSkA April 6, 2020 6:22 am #CBD #Hemp

Hemp Oil Market Current Scenario; Who will Surpass 2026 |Hemp Oil Canada Inc, Medical …

Hemp Oil Market Current Scenario; Who will Surpass 2026 |Hemp Oil Canada Inc, Medical … At present, the market is developing its presence and some of the Global Hemp Oil Market key players Involved in the study are Isodiol International Inc, … <b>Hemp</b> Oil Market Current Scenario; Who will Surpass 2026 |<b>Hemp</b> Oil Canada Inc, Medical ... https://www.google.com/url?rct=j&sa=t&url=https://sciencein.me/2020/04/06/hemp-oil-market-current-scenario-who-will-surpass-2026-hemp-oil-canada-inc-medical-marijuana-inc-folium-biosciences-cv-sciences-inc-pharmahemp-d-o-o-gaia-botanicals-llc-canazil-kazmira/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEh0GjG1sidaObX7pgq46vQlg_Obg April 6, 2020 6:11 am #CBD #Hemp

Discover aspects of the Hemp Hurd Market 2020-2026

Discover aspects of the Hemp Hurd Market 2020-2026 Global Hemp Hurd Market 2020 Economic Growth, Sales, Growth Opportunities, Demand, Size, Share, Forecast to 2026. The report studies essential … Discover aspects of the <b>Hemp</b> Hurd Market 2020-2026 https://www.google.com/url?rct=j&sa=t&url=https://www.whatech.com/market-research/agriculture/644927-discover-aspects-of-the-hemp-hurd-market-2020-2026&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFC7dL86ZGlGPrnTSADPEWnz-PjzQ April 6, 2020 4:18 am #CBD #Hemp

Total CBD makes hand sanitizer to help fill void

Total CBD makes hand sanitizer to help fill void That's because ethanol is the main ingredient required in hand sanitizer and they also use ethanol to extract CBD from the hemp leaf. Now, they're … Total <b>CBD</b> makes hand sanitizer to help fill void https://www.google.com/url?rct=j&sa=t&url=https://www.wthr.com/article/total-cbd-makes-hand-sanitizer-help-fill-void&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGONcjApzz_YaN_oA4ZnbSRFPsaqw April 6, 2020 3:33 am #CBD #Hemp

Full Spectrum 500 MG CBD Oils

Full Spectrum 500 MG CBD Oils Refined from hemp grown in America by family farmers, our CBD oil is highly potent, less than o.3% THC and tested by third-party labs at a level of 99.8 … Full Spectrum 500 MG <b>CBD</b> Oils https://www.google.com/url?rct=j&sa=t&url=https://medicalmary.com/product/full-spectrum-500-mg-cbd-oils/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEVa_eBd2ZLY36qAloF-wGYotOb6A April 6, 2020 1:09 am #CBD #Hemp

Business owner gives back to local moms amid Coronavirus pandemic

Business owner gives back to local moms amid Coronavirus pandemic Kota Organics is a hemp wellness shop. Fellman says her CBD products have helped clients with anxiety, depression and PTSD. That's why she teamed … Business owner gives back to local moms amid Coronavirus pandemic https://www.google.com/url?rct=j&sa=t&url=https://www.kvrr.com/2020/04/05/business-owner-gives-back-to-local-moms-amid-coronavirus-pandemic/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHwxK1itwhmcif4SaQEdOwo7Fj0wg April 5, 2020 10:18 pm #CBD #Hemp

The 10 Best Award-Winning Plant-Based Products You Need to Try Now

The 10 Best Award-Winning Plant-Based Products You Need to Try Now The key is their CBD (and other cannabinoids) from organically grown hemp plus added ingredients like chamomile, lemon balm extracts and L- … The 10 Best Award-Winning Plant-Based Products You Need to Try Now https://www.google.com/url?rct=j&sa=t&url=https://thebeet.com/the-10-best-award-winning-plant-based-products-you-need-to-try-now/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHf7kfy0RKVWpvxEWat_UyrhnsHbw April 5, 2020 9:45 pm #CBD #Hemp

The Complex Relationship Between Marijuana and Immune System

The Complex Relationship Between Marijuana and Immune System The ones that attract both scientific and consumer attention are, beyond doubt, cannabidiol (CBD) and delta-9-tetrahydro-cannabinol (THC). The Complex Relationship Between Marijuana and Immune System https://www.google.com/url?rct=j&sa=t&url=https://loudcloudhealth.com/marijuana-and-immune-system/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGJs7JGUMtcjPWELpc-t4UNW8kKpw April 5, 2020 9:22 pm #CBD #Hemp

Marc Narrie CEO of Buddha Beans: using CBG/CBD infused Coffee to make sure you #staygrounded

Marc Narrie CEO of Buddha Beans: using CBG/CBD infused Coffee to make sure you #staygrounded What is that?” Well in simplest terms, It is similar to CBD in many health perspectives such as it relieving anxiety and inducing calmness also by means … Marc Narrie CEO of Buddha Beans: using CBG/<b>CBD</b> infused Coffee to make sure you #staygrounded https://www.google.com/url?rct=j&sa=t&url=https://www.homeofscience.net/2020/04/05/marc-narrie-ceo-of-buddha-beans-using-cbg-cbd-infused-coffee-to-make-sure-you-staygrounded/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGfadudUHDSEfM8Vow9u2Um6SAgmg April 5, 2020 8:03 pm #CBD #Hemp

Freddie Flintoff admits he's hooked to CBD oil-infused chocolate nut butter

Freddie Flintoff admits he's hooked to CBD oil-infused chocolate nut butter The cricket legend and Top Gear host has revealed he discovered the legal hemp and cannabidiol-filled snack online. He said: “CBD oil nut butter. This … Freddie Flintoff admits he's hooked to <b>CBD</b> oil-infused chocolate nut butter https://www.google.com/url?rct=j&sa=t&url=https://www.dailystar.co.uk/sport/freddie-flintoff-admits-hes-hooked-21818139&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFDuya8DO3koe8T0_oM9AdGaBHYNg April 5, 2020 8:03 pm #CBD #Hemp

Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967.

Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967.

Related Articles

Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967.

Int J Mol Sci. 2020 Apr 01;21(7):

Authors: Mason ER, Cummins TR

Abstract
Many epilepsy patients are refractory to conventional antiepileptic drugs. Resurgent and persistent currents can be enhanced by epilepsy mutations in the Nav1.2 channel, but conventional antiepileptic drugs inhibit normal transient currents through these channels, along with aberrant resurgent and persistent currents that are enhanced by Nav1.2 epilepsy mutations. Pharmacotherapies that specifically target aberrant resurgent and/or persistent currents would likely have fewer unwanted side effects and be effective in many patients with refractory epilepsy. This study investigated the effects of cannbidiol (CBD) and GS967 (each at 1 μM) on transient, resurgent, and persistent currents in human embryonic kidney (HEK) cells stably expressing wild-type hNav1.2 channels. We found that CBD preferentially inhibits resurgent currents over transient currents in this paradigm; and that GS967 preferentially inhibits persistent currents over transient currents. Therefore, CBD and GS967 may represent a new class of more targeted and effective antiepileptic drugs.

PMID: 32244818 [PubMed – as supplied by publisher]

Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967. https://www.ncbi.nlm.nih.gov/pubmed/32244818?dopt=Abstract #CBD #Hemp

CBD Reverts the Mesenchymal Invasive Phenotype of Breast Cancer Cells Induced by the Inflammatory Cytokine IL-1β.

CBD Reverts the Mesenchymal Invasive Phenotype of Breast Cancer Cells Induced by the Inflammatory Cytokine IL-1β.

Related Articles

CBD Reverts the Mesenchymal Invasive Phenotype of Breast Cancer Cells Induced by the Inflammatory Cytokine IL-1β.

Int J Mol Sci. 2020 Mar 31;21(7):

Authors: García-Morales L, Castillo AM, Tapia Ramírez J, Zamudio-Meza H, Domínguez-Robles MDC, Meza I

Abstract
Cannabidiol (CBD) has been used to treat a variety of cancers and inflammatory conditions with controversial results. In previous work, we have shown that breast cancer MCF-7 cells, selected by their response to inflammatory IL-1β cytokine, acquire a malignant phenotype (6D cells) through an epithelial-mesenchymal transition (EMT). We evaluated CBD as a potential inhibitor of this transition and inducer of reversion to a non-invasive phenotype. It decreased 6D cell viability, downregulating expression of receptor CB1. The CBD blocked migration and progression of the IL-1β-induced signaling pathway IL-1β/IL-1RI/β-catenin, the driver of EMT. Cannabidiol reestablished the epithelial organization lost by dispersion of the cells and re-localized E-cadherin and β-catenin at the adherens junctions. It also prevented β-catenin nuclear translocation and decreased over-expression of genes for ∆Np63α, BIRC3, and ID1 proteins, induced by IL-1β for acquisition of malignant features. Cannabidiol inhibited the protein kinase B (AKT) activation, a crucial effector in the IL-1β/IL-1RI/β-catenin pathway, indicating that at this point there is crosstalk between IL-1β and CBD signaling which results in phenotype reversion. Our 6D cell system allowed step-by-step analysis of the phenotype transition and better understanding of mechanisms by which CBD blocks and reverts the effects of inflammatory IL-1β in the EMT.

PMID: 32244518 [PubMed – as supplied by publisher]

CBD Reverts the Mesenchymal Invasive Phenotype of Breast Cancer Cells Induced by the Inflammatory Cytokine IL-1β. https://www.ncbi.nlm.nih.gov/pubmed/32244518?dopt=Abstract #CBD #Hemp

Vegan Sun-Dried Tomato Mac N Cheez Recipe

Vegan Sun-Dried Tomato Mac N Cheez Recipe I like to top it with hemp seeds for a little extra texture and nutrition, but that's totally optional. Use chickpea or lentil pasta to make this mac 'n cheez … Vegan Sun-Dried Tomato Mac N Cheez Recipe https://www.google.com/url?rct=j&sa=t&url=https://vegoutmag.com/losangeles/recipe.php%3Fid%3D11&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFaKJr-a8lrJoakmb-qeaNYs5BNNA April 5, 2020 6:06 pm #CBD #Hemp

The Week In Cannabis: Stocks Back In The Red, CannTrust Enters Creditor Protection, Good News …

The Week In Cannabis: Stocks Back In The Red, CannTrust Enters Creditor Protection, Good News … The program was created to aid hemp farmers during this growing season, which has been impacted by COVID-19, by providing competitively priced … The Week In Cannabis: Stocks Back In The Red, CannTrust Enters Creditor Protection, Good News ... https://www.google.com/url?rct=j&sa=t&url=https://www.benzinga.com/markets/cannabis/20/04/15745871/the-week-in-cannabis-stocks-back-in-the-red-canntrust-enters-creditor-protection-good-news-for-m&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGc7j1p7pYHc0aOraOdorr06pAw3w April 5, 2020 5:26 pm #CBD #Hemp

New printable coupons: Benadryl, Claritin, Zyrtec, Colgate, Garnier, Covergirl, feminine products

New printable coupons: Benadryl, Claritin, Zyrtec, Colgate, Garnier, Covergirl, feminine products $1/1 Colgate toothpaste, select varieties (Enamel Health, Charcoal, Hemp Seed, Sensitive). $1/1 Adult Benadryl. $1/1 Garnier Fructis shampoo, … New printable coupons: Benadryl, Claritin, Zyrtec, Colgate, Garnier, Covergirl, feminine products https://www.google.com/url?rct=j&sa=t&url=https://www.wral.com/new-printable-coupons-benadryl-claritin-zyrtec-colgate-garnier-covergirl-feminine-products/19043312/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGTOdd3RLobf8OSakmHrNUHIOeBdQ April 5, 2020 4:41 pm #CBD #Hemp

What is Tincture and How does it work with CBD?

What is Tincture and How does it work with CBD? Among the hundred, CBD or Cannabidiol is the most prominent cannabinoid. It is the therapeutic compound that gives cannabis its medicinal properties. What is Tincture and How does it work with <b>CBD</b>? https://www.google.com/url?rct=j&sa=t&url=https://ventsmagazine.com/2020/04/05/what-is-tincture-and-how-does-it-work-with-cbd/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEuKGtYBTsTZlRPAHIp3_1RvVp-9w April 5, 2020 4:41 pm #CBD #Hemp

Police Drop Charges Against Hemp Farmers

Police Drop Charges Against Hemp Farmers After being notified of the crops, authorities took samples and tested them for THC. No active THC was found in the plants; industrial hemp contains very … Police Drop Charges Against <b>Hemp</b> Farmers https://www.google.com/url?rct=j&sa=t&url=https://www.icelandreview.com/news/police-drop-charges-against-hemp-farmers/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEtxYFdP9T_T70Oqkg3Z5VLqZSlOg April 5, 2020 3:33 pm #CBD #Hemp

HB484

HB484 HB 484 Hemp products; regulation, labeling. … Services to adopt regulations prohibiting the use of the term “CBD” in connection with a hemp product, … HB484 https://www.google.com/url?rct=j&sa=t&url=https://lis.virginia.gov/cgi-bin/legp604.exe%3F201%2Bsum%2BHB484%26201%2Bsum%2BHB484&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFFGx68-PA65LM43RJ_SQa8KbuY7w April 5, 2020 3:25 pm #CBD #Hemp

i3G Media Takes Home Sevareid Awards

i3G Media Takes Home Sevareid Awards Warren Abrahamson received merit for his hard feature “Interest in Hemp, CBD Growing in Jamestown” in the small market category. “I'm honored to … i3G Media Takes Home Sevareid Awards https://www.google.com/url?rct=j&sa=t&url=https://www.newsdakota.com/2020/04/05/i3g-media-takes-home-sevareid-awards/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHUi4xt-pnEhMUKndDMUBLzTeUmog April 5, 2020 3:00 pm #CBD #Hemp

The Downside of Narrowly Focused Cannabis Operations

The Downside of Narrowly Focused Cannabis Operations The hemp industry in Europe is very different from its counterpart in North America. In this webinar we invited Yannik Schlup, Chief Business Officer of … The Downside of Narrowly Focused Cannabis Operations https://www.google.com/url?rct=j&sa=t&url=https://www.newcannabisventures.com/the-downside-of-narrowly-focused-cannabis-operations/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFNl6YedSQU3K5vNBDUG4aYWwaJpQ April 5, 2020 2:48 pm #CBD #Hemp

Cbd Pm

Cbd Pm Duos frowned It really makes people listen to you. Although it is possible to keep all cbd pm records hemp for pain of the Bank of China in 2000, it is … <b>Cbd</b> Pm https://www.google.com/url?rct=j&sa=t&url=https://www.mosquefoundation.org/cbd-oil/cbd-pm&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFSuf1tto3nf9nw1skCZ05pWAN0Dw April 5, 2020 2:14 pm #CBD #Hemp

Let's Eat: Inspired Alchemy's superfood-infused truffles satisfy body and mind

Let's Eat: Inspired Alchemy's superfood-infused truffles satisfy body and mind Saia uses CBD (cannabidiol) oil to manage pain from an accident; her daughter uses it for anxiety. Inspired Alchemy currently makes three different CBD … Let's Eat: Inspired Alchemy's superfood-infused truffles satisfy body and mind https://www.google.com/url?rct=j&sa=t&url=https://madison.com/entertainment/dining/restaurants/lets-eat-inspired-alchemys-superfood-infused-truffles-satisfy-body-and-mind/article_99b09480-60c4-5a39-a545-08f7a26af8f3.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFQAQ1xcf-qNrvpQ_0n3pfgOYLXNQ April 5, 2020 12:56 pm #CBD #Hemp

en Kenzi on Twitter

“@WHO considers #THC useful in “decreasing pain intensity, as an adjunct to opioids”. To avoid #shortage in opioid pain medication, healthcare systems should explore the use of #cannabinoids as complement. Adapt posology in non-#COVID19 patients & redirect #opioids to +urgent needs”

en Kenzi on Twitter
“@INCB_President @WHO considers #THC useful in “decreasing pain intensity, as an adjunct to opioids” To avoid #shortage in opioid pain medication, healthcare systems should explore the use of #cannabinoids as complement. Adapt posology in non-#COVID19 patients & redirect #opioids to +urgen…

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en Kenzi on Twitter

April 5, 2020 12:38 pm

Amid coronavirus, these Southern Tier companies have started making hand sanitizer

Amid coronavirus, these Southern Tier companies have started making hand sanitizer People Grow Together's spectrum of products ranges from hemp oil to post-tattoo salve to anti-aging soap to pet treats, all born of agricultural hemp … Amid coronavirus, these Southern Tier companies have started making hand sanitizer https://www.google.com/url?rct=j&sa=t&url=https://www.ithacajournal.com/story/news/local/2020/04/05/coronavirus-binghamton-windsor-people-grow-together-apalachin-waterman-distillery-hand-sanitizer/2943278001/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHPekffVoIxPpmWiccOaZJATcLlow April 5, 2020 12:00 pm #CBD #Hemp

Coronavirus live blog: Sunday April 5, 2020

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Prolonged oral transmucosal delivery of highly lipophilic drug cannabidiol.

Prolonged oral transmucosal delivery of highly lipophilic drug cannabidiol.

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Prolonged oral transmucosal delivery of highly lipophilic drug cannabidiol.

Int J Pharm. 2020 Mar 31;:119276

Authors: Itin C, Barasch D, Domb AJ, Hoffman A

Abstract
Delivery of drugs through oral mucosa enables bypass of the gastrointestinal tract and “first pass” metabolism in the liver and the gut. Thus, a higher and less variable bioavailability can be obtained. Mechanisms of this administration route for cannabidiol were investigated in the current research in pigs. Results show that cannabidiol has substantially low permeability rate over 8 hours through oral mucosa and accumulates significantly within it. Furthermore, following the removal of the delivery device, residual prolongation of release from the oral mucosa into systemic blood circulation continues for several hours. This method of delivery enabled acquisition of clinically relevant plasma levels of cannabidiol. The absorption profile indicates that cannabidiol, as well as other lipophilic molecules, should be delivered through oral mucosa for systemic absorption from a device that conceals the drug and prevents its washout by the saliva flow and subsequent ingestion into gastrointestinal tract.

PMID: 32243971 [PubMed – as supplied by publisher]

Prolonged oral transmucosal delivery of highly lipophilic drug cannabidiol. https://www.ncbi.nlm.nih.gov/pubmed/32243971?dopt=Abstract #CBD #Hemp

MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages.

MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages.

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MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages.

J Neuroimmunol. 2020 Mar 20;343:577217

Authors: Fitzpatrick JM, Minogue E, Curham L, Tyrrell H, Gavigan P, Hind W, Downer EJ

Abstract
Toll-like receptors (TLRs) are sensors of pathogen-associated molecules that trigger inflammatory signalling in innate immune cells including macrophages. All TLRs, with the exception of TLR3, promote intracellular signalling via recruitment of the myeloid differentiation factor 88 (MyD88) adaptor, while TLR3 signals via Toll-Interleukin-1 Receptor (TIR)-domain-containing adaptor-inducing interferon (IFN)-β (TRIF) adaptor to induce MyD88-independent signalling. Furthermore, TLR4 can activate both MyD88-dependent and -independent signalling (via TRIF). The study aim was to decipher the impact of the highly purified plant-derived (phyto) cannabinoids Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), when delivered in isolation and in combination (1:1), on MyD88-dependent and -independent signalling in macrophages. We employed the use of the viral dsRNA mimetic poly(I:C) and endotoxin lipopolysaccharide (LPS), to induce viral TLR3 and bacterial TLR4 signalling in human Tamm-Horsfall protein-1 (THP-1)-derived macrophages, respectively. TLR3/TLR4 stimulation promoted the activation of interferon (IFN) regulatory factor 3 (IRF3) and TLR4 promoted the activation of nuclear factor (NF)-κB signalling, with downstream production of the type I IFN-β, the chemokines CXCL10 and CXCL8, and cytokine TNF-α. THC and CBD (both at 10 μM) attenuated TLR3/4-induced IRF3 activation and induction of CXCL10/IFN-β, while both phytocannabinoids failed to impact TLR4-induced IκB-α degradation and TNF-α/CXCL8 expression. The role of CB1, CB2 and PPARγ receptors in mediating the effect of THC and CBD on MyD88-independent signalling was investigated. TLRs are attractive therapeutic targets given their role in inflammation and initiation of adaptive immunity, and data herein indicate that both CBD and THC preferentially modulate TLR3 and TLR4 signalling via MyD88-independent mechanisms in macrophages. This offers mechanistic insight into the role of phytocannabinoids in modulating cellular inflammation.

PMID: 32244040 [PubMed – as supplied by publisher]

MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages. https://www.ncbi.nlm.nih.gov/pubmed/32244040?dopt=Abstract #CBD #Hemp

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Halo Announces Proposed Acquisition of Nasalbinoid Natural Devices and Concurrent Private … Nasalbinoid is focused on the development of an innovative line of all natural and refreshing personal nasal inhalers infused with cannabidiol (“CBD”) … Halo Announces Proposed Acquisition of Nasalbinoid Natural Devices and Concurrent Private ... https://www.google.com/url?rct=j&sa=t&url=http://www.oleantimesherald.com/business/halo-announces-proposed-acquisition-of-nasalbinoid-natural-devices-and-concurrent-private-placement/article_68a94a32-7e51-5fe4-af7e-506efa76a704.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHUAvY3OBkllQqnG-jupGsPbTTDZw April 4, 2020 3:22 am #CBD #Hemp

Hemp industry could see economic impact from COVID-19

Hemp industry could see economic impact from COVID-19 (WHSV) — Despite concerns of the economy during the pandemic, the hemp industry aims to keep trending up. Glenn Rodes of Riverhill Farms in Port … <b>Hemp</b> industry could see economic impact from COVID-19 https://www.google.com/url?rct=j&sa=t&url=https://www.whsv.com/content/news/Hemp-industry-could-see-economic-impact-from-COVID-19.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNF86_Wc1H5MVCBJIvv8cN6YbFl3Bg April 4, 2020 2:37 am #CBD #Hemp

Industrial Hemp Market Forecast and Segments, 2019-2029

Industrial Hemp Market Forecast and Segments, 2019-2029 The research study has been prepared with the use of in-depth qualitative and quantitative analyses of the global Industrial Hemp market. We have … Industrial <b>Hemp</b> Market Forecast and Segments, 2019-2029 https://www.google.com/url?rct=j&sa=t&url=https://www.curiousdesk.com/industrial-hemp-market-forecast-and-segments-2019-2029/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNFvSdRPB9QrKkPMyclhuPslw-eIjw April 4, 2020 12:00 am #CBD #Hemp

We're Open 518: Health & Wellness

We're Open 518: Health & Wellness Your CBD Store East Greenbush 598 Columbia TurnpikeHannaford … We use only Organic non-GMO industrial hemp grown in Colorado which has … We're Open 518: Health & Wellness https://www.google.com/url?rct=j&sa=t&url=https://cbs6albany.com/community/were-open-518/were-open-518-health-wellness&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEQi8NRkqWee-Xv63UocG2EZN9wBQ April 3, 2020 10:55 pm #CBD #Hemp

Alaska's hemp industry set to go live through online-only registrations

Alaska's hemp industry set to go live through online-only registrations Farmers, processors and retailers in Alaska can start applying for hemp registrations Monday after the industry officially launches on April 4. Due to the … Alaska's <b>hemp</b> industry set to go live through online-only registrations https://www.google.com/url?rct=j&sa=t&url=https://hempindustrydaily.com/alaskas-hemp-industry-set-to-go-live-through-online-only-registrations/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNF2dkwn2fT4OQ4WG1D5XKIjghBVAA April 3, 2020 9:56 pm #CBD #Hemp

Designer Says Pure Spectrum CBD Stole Branding IP

Designer Says Pure Spectrum CBD Stole Branding IP A designer has sued Pure Spectrum CBD in Colorado federal court for more than $900,000, claiming the company stole her branding designs after misleading her on the compensation and company equity stake it would give her for her work. Designer Says Pure Spectrum CBD Stole Branding IP https://www.law360.com/cannabis/articles/1260322?utm_source=rss&utm_medium=rss&utm_campaign=section April 3, 2020 9:49 pm #CBD #Hemp

Cbd Nashville

Cbd Nashville How Does Hemp Oil Help Your Health –cbd? Sleep, Isa. Aunt Bao cbd nashville said, I hope long cbd nashville sleep can wash away wonder cbd oil Ru … <b>Cbd</b> Nashville https://www.google.com/url?rct=j&sa=t&url=https://www.migrainetrust.org/cbd-oil/cbd-nashville&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNGVPx9Rg4BvfrpRovwpourU2pSMBA April 3, 2020 9:25 pm #CBD #Hemp

Editor's Pick: Best Full Spectrum Hemp Oil Tincture – CBDistillery™

Editor's Pick: Best Full Spectrum Hemp Oil Tincture – CBDistillery™ Before I began using CBD oil, each scenario by itself would leave me sleepless – all put together I would have been practically nonfunctional. Yet this … Editor's Pick: Best Full Spectrum <b>Hemp</b> Oil Tincture – CBDistillery™ https://www.google.com/url?rct=j&sa=t&url=https://www.laweekly.com/editors-pick-best-full-spectrum-hemp-oil-tincture-cbdistillery/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHQVbFygoa4gAEGtVxXbYmAcVZL4w April 3, 2020 9:22 pm #CBD #Hemp

Two Canadian plant companies form JV to supply 12 million hemp clones from tissue culture

Two Canadian plant companies form JV to supply 12 million hemp clones from tissue culture Hemp growers will have more young plant options to choose from as a result of a new joint venture between Vancouver-based plant company 3 … Two Canadian plant companies form JV to supply 12 million <b>hemp</b> clones from tissue culture https://www.google.com/url?rct=j&sa=t&url=https://hempindustrydaily.com/two-canadian-plant-companies-form-jv-to-supply-12-million-hemp-clones-from-tissue-culture/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNEAQsuMYXh2yx62JNv9SiyraWsPXQ April 3, 2020 8:48 pm #CBD #Hemp

Kombrewcha Co-Founder Launches DTC Hemp-Infused Oat Milk Lattes

Kombrewcha Co-Founder Launches DTC Hemp-Infused Oat Milk Lattes Glazer ultimately broke his first promise while keeping the second: His new venture is LaDiDa, a line of hemp-infused oat milk canned lattes which … Kombrewcha Co-Founder Launches DTC <b>Hemp</b>-Infused Oat Milk Lattes https://www.google.com/url?rct=j&sa=t&url=https://www.bevnet.com/news/2020/kombrewcha-co-founder-launches-dtc-hemp-infused-oat-milk-lattes&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNH5ozx1znrtDmEb6lAak5d6y2n0qQ April 3, 2020 8:48 pm #CBD #Hemp

Carolina Hemp Company – Youngsville, NC

Carolina Hemp Company – Youngsville, NC Stop by our franchise location at 119. E Main St in Youngsville, NC 27596 and enjoy a free sample of our Carolina Hemp Naturals Whole-Spectrum … Carolina <b>Hemp</b> Company - Youngsville, NC https://www.google.com/url?rct=j&sa=t&url=https://www.facebook.com/TheGreatCarolinaHempCompany/videos/carolina-hemp-company-youngsville-nc/847177555718151/%3F__so__%3Dpermalink%26__rv__%3Drelated_videos&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNF8jge71Mnepwpb1Zy2XopsKfTZMw April 3, 2020 8:20 pm #CBD #Hemp

De-stress with oHHo CBD

De-stress with oHHo CBD Unlike other CBD oils, oHHo only contains two ingredients — both of which you can spell—hemp extract and MCT oil,” said Stephenson.”Depending on … De-stress with oHHo <b>CBD</b> https://www.google.com/url?rct=j&sa=t&url=https://vmagazine.com/article/de-stress-with-ohho-cbd/&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNH22LUu4dmgL3kAL6gPSg12YKFhFA April 3, 2020 7:52 pm #CBD #Hemp

Pot Co. Acreage Scraps $120M Deal Amid Virus Cutbacks

Pot Co. Acreage Scraps $120M Deal Amid Virus Cutbacks Cannabis company Acreage Holdings Inc. announced Friday that it has terminated a $120 million deal to acquire Nevada-based marijuana cultivator and manufacturer Deep Roots Medical LLC, among other company cutbacks, citing a significant impact from the coronavirus pandemic. Pot Co. Acreage Scraps 0M Deal Amid Virus Cutbacks https://www.law360.com/cannabis/articles/1260354?utm_source=rss&utm_medium=rss&utm_campaign=section April 3, 2020 7:49 pm #CBD #Hemp

Hemp Depot Pivots Production, Starts Making Hand Sanitizer Amid COVID-19 Outbreak

Hemp Depot Pivots Production, Starts Making Hand Sanitizer Amid COVID-19 Outbreak Hemp Depot produces hemp CBD wholesale, but as COVID-19 became a pandemic, wholesale orders dropped rapidly, thus creating a need for CEO … <b>Hemp</b> Depot Pivots Production, Starts Making Hand Sanitizer Amid COVID-19 Outbreak https://www.google.com/url?rct=j&sa=t&url=https://www.benzinga.com/markets/cannabis/20/04/15742320/hemp-depot-pivots-production-starts-making-hand-sanitizer-amid-covid-19-outbreak&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHp1TXCjFYfqSWXS4bdKm33RDeXaQ April 3, 2020 7:41 pm #CBD #Hemp

Special webinar: NJ's hemp leaders to discuss industry shifts amid coronavirus crisis on April 7

Special webinar: NJ's hemp leaders to discuss industry shifts amid coronavirus crisis on April 7 On the CBD front, McQueeny told NJ Cannabis Insider he's been working with clients on how to navigate a disparity that allows liquor stores to be open … Special webinar: NJ's <b>hemp</b> leaders to discuss industry shifts amid coronavirus crisis on April 7 https://www.google.com/url?rct=j&sa=t&url=https://www.nj.com/marijuana/2020/04/special-webinar-njs-hemp-leaders-to-discuss-industry-shifts-amid-coronavirus-crisis-on-april-7.html&ct=ga&cd=CAIyGjJiMjA4MDRjNzhiYTg2MWM6Y29tOmVuOlVT&usg=AFQjCNHYW7q0Ap2M07Ri7v5_FCQUM_8vJA April 3, 2020 7:37 pm #CBD #Hemp